{
 "brief_date": "2026-10-19",
 "generated_at": "2026-10-19T07:50:01.425499+08:00",
 "window": {
  "from": "2026-10-16",
  "to": "2026-10-19"
 },
 "instructions": "这是小动物医学简报的原始素材包。只使用本文件条目生成简报：临床研究/指南与监管写中文要点、英文要点、来源与日期、证据级别、链接；疾病预警只写中文翻译+原文链接；不要编造，未提供的结论不要写。",
 "counts": {
  "clinical_research": 6,
  "guidelines_regulation": 4,
  "disease_alerts": 5
 },
 "categories": {
  "clinical_research": [
   {
    "id": "pmid:42885408",
    "source": "PubMed",
    "journal": "The Journal of small animal practice",
    "date": "2026-10-16",
    "title": "Urinary liver-type fatty acid-binding protein in cats with lower urinary tract disease.",
    "abstract": "The aim of this study was to evaluate urinary liver-type fatty acid-binding protein levels in both obstructive and non-obstructive feline lower urinary tract disease. In addition, urinary liver-type fatty acid-binding protein levels were investigated in cats experiencing short-term (<36 hours) and long-term (≥36 hours) urethral obstruction. The study included 32 cats, classified into two main groups: cats with feline lower urinary tract disease (n = 24) and healthy controls (n = 8). The feline lower urinary tract disease group was subdivided into obstructive (n = 16) and non-obstructive (n = 8) forms. The obstructive group was further divided based on urethral obstruction duration into short-term (n = 8) and long-term (n = 8) sub-subgroups. Serum creatinine, blood urea nitrogen and potassium were measured in blood samples. Urinary liver-type fatty acid-binding protein and urinary creatinine concentrations were measured in urine supernatant samples. Urinary liver-type fatty acid-binding protein concentrations were indexed to urinary creatinine and expressed as the urinary liver-type fatty acid-binding protein/creatinine ratio. The mean urinary liver-type fatty acid-binding protein/creatinine values of cats with obstructive feline lower urinary tract disease were statistically higher than those in cats with non-obstructive feline lower urinary tract disease and healthy controls. The difference between the mean urinary liver-type fatty acid-binding protein/creatinine values of cats with long-term and short-term obstruction was not statistically significant. In addition, modera",
    "url": "https://pubmed.ncbi.nlm.nih.gov/42885408/",
    "doi": "10.1111/jsap.70212",
    "pmid": "42885408",
    "authors": [
     "N Culha",
     "A Acar",
     "B Ulutas"
    ],
    "collected_by": "pubmed_core",
    "priority": 99
   },
   {
    "id": "pmid:42050858",
    "source": "PubMed",
    "journal": "The Veterinary record",
    "date": "2026-10-17",
    "title": "Evaluation of thyroglobulin autoantibodies in dogs at the time of diagnosis of hypoadrenocorticism and during treatment.",
    "abstract": "Autoimmune thyroiditis (AIT) may occur more frequently in dogs with hypoadrenocorticism (HA) than previously recognised. The objective of this study was to determine the presence of thyroglobulin autoantibodies (TgAAs) in dogs with HA. Dogs were included if HA was confirmed by an adrenocorticotropic hormone stimulation test conducted between 2019 and 2023. Serum total thyroxine, thyrotropin and TgAA were analysed from samples taken before and during HA treatment. Thirty-seven dogs were enrolled, with nine dogs showing positive TgAA titres at enrolment. Following HA treatment, TgAA became undetectable in six dogs; two showed persistent positive TgAA results and one was lost to follow-up. Additionally, two dogs that were initially TgAA negative developed hypothyroidism during the follow-up period. The overall prevalence of concurrent HA and hypothyroidism after initiation of hormone replacement therapy was three of 30 among the dogs for which follow-up data were available. The retrospective nature of the study, small sample size and incomplete follow-up data for some patients limit the conclusions that can be drawn. Our findings demonstrate the concurrent occurrence of two different autoimmune diseases, AIT and HA, and show that the presence of TgAA can completely resolve with cortisol replacement therapy. Therefore, it is recommended to reassess thyroid function after initiating HA treatment to avoid unnecessary lifelong thyroxine supplementation.",
    "url": "https://pubmed.ncbi.nlm.nih.gov/42050858/",
    "doi": "10.1002/vetr.70622",
    "pmid": "42050858",
    "authors": [
     "Christin Emming",
     "Sina Strey",
     "Ina Leiter"
    ],
    "collected_by": "pubmed_core",
    "priority": 86
   },
   {
    "id": "pmid:41491344",
    "source": "PubMed",
    "journal": "The Veterinary record",
    "date": "2026-10-17",
    "title": "Transpalpebral exenteration in dogs: A retrospective study (2003‒2023).",
    "abstract": "Transpalpebral exenteration is indicated in cases of neoplasia, infection or severe trauma involving the globe and orbit. Limited peer-reviewed literature exists on the indications, complications and outcomes associated with this procedure in dogs. This retrospective study analysed medical records of 35 dogs undergoing transpalpebral exenteration at three UK veterinary referral centres between 2003 and 2023. The data included signalment, diagnostic findings, surgical details and postoperative complications. Kruskal‒Wallis and Fisher's exact tests were used to analyse relationships between clinical variables and complications. Orbital neoplasia was the most common indication (54.3%, 19/35), followed by orbital inflammatory disease (25.7%, 9/35), orbital cyst (11.4%, 4/35), orbital foreign body (5.7%, 2/35) and orbital pseudotumour (2.9%, 1/35). Immediate postoperative complications (21 days) complications occurred in 20% (7/35) and 5.7% (2/35) of cases, respectively. Six patients (17.1%) required additional treatment. No significant correlations were found between the independent variables and complication rates. This study is limited by its retrospective nature and the small sample size. Transpalpebral exenteration is a safe procedure with primarily minor postoperative complications that typically resolve without intervention.",
    "url": "https://pubmed.ncbi.nlm.nih.gov/41491344/",
    "doi": "10.1002/vetr.70219",
    "pmid": "41491344",
    "authors": [
     "Kayal Patel",
     "Rodrigo Pinheiro de Lacerda",
     "Samuela Mazzucchelli"
    ],
    "collected_by": "pubmed_core",
    "priority": 86
   },
   {
    "id": "pmid:41427741",
    "source": "PubMed",
    "journal": "The Veterinary record",
    "date": "2026-10-17",
    "title": "Sensory profile of cats with potential pain-related diabetic neuropathy.",
    "abstract": "Diabetes mellitus (DM) can cause peripheral neuropathy. This study aimed to evaluate sensory function by measuring the mechanical nociceptive thresholds (MNT) and diffuse noxious inhibitory control (DNIC) of cats with diabetes mellitus (DMcats). Eight cats with DM and 12 healthy controls were included in a prospective, randomised study. MNT were measured by applying pressure against the metatarsal pad (MNTbio). MNT were also measured using a mechanical actuator attached to one of the cat's pelvic limbs (MNTtop). The DNIC was assessed by comparing MNTtop before and after a conditioning stimulus. MNTbio of the controls were significantly lower (2.1 ± 0.7 N) than those of DMcats (3.6 ± 1.2 N). DNIC and MNTtop were not different between groups. This study had a small cohort of patients and an MNT cut-off to prevent injuries. DMcats showed hypoalgesia and loss of sensory function. This study could not differentiate DNIC between healthy and those with DM.",
    "url": "https://pubmed.ncbi.nlm.nih.gov/41427741/",
    "doi": "10.1002/vetr.70227",
    "pmid": "41427741",
    "authors": [
     "Hélène L M Ruel",
     "Vanessa Bruneau",
     "Berenice Conversy"
    ],
    "collected_by": "pubmed_core",
    "priority": 86
   },
   {
    "id": "pmid:42885475",
    "source": "PubMed",
    "journal": "Veterinary dermatology",
    "date": "2026-10-16",
    "title": "Clinical Characteristics of Hair Cycle Arrest in Toy Poodles: A Retrospective Comparison With Pomeranians.",
    "abstract": "Hair cycle arrest (HCA), known as alopecia X, is an alopecia disorder most commonly reported in Nordic breeds-particularly Pomeranians. Toy poodles (TPs) also are frequently affected, yet their clinical characteristics have not been reviewed systematically. The aim of this retrospective case series was to compare the clinical characteristics of HCA in TPs and Pomeranians. Medical records of client-owned dogs diagnosed with HCA between 2018 and 2024 were reviewed. Signalment, including age of onset and age at diagnosis, clinical features, skin barrier function (transepidermal water loss [TEWL], stratum corneum hydration [SCH]) and treatment outcomes were analysed. Fifty dogs (19 TPs, 31 Pomeranians) met the inclusion criteria. TPs were significantly older than Pomeranians both at disease onset and at the first presentation (p = 0.003 and p = 0.001, respectively). Both breeds exhibited similar bilateral symmetrical alopecia presentations; however, Pomeranians mainly presented with a single alopecic site, while nearly half of the TPs had multiple affected sites (p = 0.032). Pruritus and superficial pyoderma were common in both breeds. TEWL and SCH values frequently deviated from reference ranges (increased TEWL and decreased SCH), indicating impaired skin barrier function. TEWL was significantly higher in TPs with pyoderma than in those without (p = 0.025). Regarding outcomes, > 70% of patients showed partial or complete regrowth, despite various treatment regimens. HCA in TPs closely resembles that in Pomeranians, despite genetic divergence, suggesting a conserved pathogenesi",
    "url": "https://pubmed.ncbi.nlm.nih.gov/42885475/",
    "doi": "10.1111/vde.70134",
    "pmid": "42885475",
    "authors": [
     "Akira Ueyama",
     "Hazumu Amatuji",
     "Keita Iyori"
    ],
    "collected_by": "pubmed_core",
    "priority": 69
   },
   {
    "id": "pmid:42886669",
    "source": "PubMed",
    "journal": "PloS one",
    "date": "2026-01-01",
    "title": "Molecular screening of selected RNA viruses in neotropical wild felids of Brazil.",
    "abstract": "Astrovirus, cardiovirus and rotavirus are RNA viruses widely distributed among humans, domestic and wild mammals, including felids, occasionally associated with fatal outbreaks and highly resistant to environmental conditions. Despite this, there are no reports of these viruses in New World felids. The aim of this study was to investigate the presence of astrovirus, rotavirus and cardiovirus in non-domestic felids under human care or in the wild, across multiple Brazilian biomes (i.e., Amazon Forest, Atlantic Forest, Caatinga, and Cerrado). Biological samples (e.g., blood, oral and rectal swabs, and frozen tissues) were submitted to reverse transcriptase polymerase chain reaction (RT-PCR) for astrovirus detection and real-time RT-PCR for rotavirus and cardiovirus, followed by sequencing. Fifty wild felids were analyzed, comprising 40 free-ranging and 10 captive animals: 19 ocelots (Leopardus pardalis), 12 pumas (Puma concolor), seven jaguarundis (Herpailurus yagouaroundi), six southern tiger cats (Leopardus guttulus), three margays (Leopardus wiedii) and three jaguars (Panthera onca). An astrovirus was detected in rectal swab of a healthy captive southern tiger cat, while a genotype G3P[3] Rotavirus alphagastroenteritidis (Rotavirus A) was detected in intestine of a roadkill puma. All felid samples were negative for cardiovirus. Morphological analyses of available formalin-fixed tissues of the rotavirus-positive puma were inconclusive due to autolysis. To the authors' knowledge, this is the first molecular detection of astrovirus and rotavirus in Neotropical wild felid spec",
    "url": "https://pubmed.ncbi.nlm.nih.gov/42886669/",
    "doi": "10.1371/journal.pone.0359169",
    "pmid": "42886669",
    "authors": [
     "Michelle Colpani",
     "Aricia Duarte-Benvenuto",
     "Carlos Sacristán"
    ],
    "collected_by": "pubmed_alerts",
    "priority": 50
   }
  ],
  "guidelines_regulation": [
   {
    "id": "fr:2026-21084",
    "source": "Federal Register / FDA",
    "journal": "Federal Register (Notice)",
    "date": "2026-10-15",
    "title": "Authorization of Emergency Use for Four Animal Drugs for the Prevention and Treatment of New World Screwworm; Availability",
    "abstract": "The Food and Drug Administration (FDA or the Agency) is announcing the issuance of four Emergency Use Authorizations (EUA or Authorization) under the Federal Food, Drug, and Cosmetic Act (FD&C Act) for new animal products. FDA has issued one EUA for an animal product as requested by Elanco US Inc. for application on or around wounds for the prevention of infestations caused by New World screwworm (Cochliomyia hominivorax; NWS) larvae (myiasis) in sheep, cattle, goats, swine, camelids, and the following captive and captured wildlife species: cervids, American bison, bighorn sheep, and Sonoran pronghorn. FDA has issued one EUA for an animal product as requested by Zoetis Inc. for the treatment of infestations caused by NWS (myiasis) in dogs and puppies. FDA has issued one EUA for an animal product as requested by Bimeda Animal Health Ltd. for the prevention of infestations caused by NWS (myiasis) in cattle. FDA has issued one EUA for an animal product as requested by Sergeant's Pet Care Products LLC for the treatment and prevention of infestations caused by NWS (myiasis) in dogs, puppies, cats and kittens 2 pounds of body weight or greater and 4 weeks of age and older. The Authorizations contain, among other things, conditions on the emergency use of the authorized products. The Authorizations follow the August 18, 2025, determination by the Secretary of Health and Human Services (HHS) that there is a significant potential for a public health emergency that has a significant potential to affect national security or the health and security of U.S. citizens living abroad and th",
    "url": "https://www.federalregister.gov/documents/2026/10/15/2026-21084/authorization-of-emergency-use-for-four-animal-drugs-for-the-prevention-and-treatment-of-new-world",
    "doi": null,
    "pmid": null,
    "document_number": "2026-21084",
    "collected_by": "federal_register",
    "priority": 0,
    "category_hint": "regulation"
   },
   {
    "id": "dvm360:https://www.dvm360.com/view/recover-first-aid-guidelines-give-veterinary-teams-a-playbook-for-coaching-clients",
    "source": "dvm360",
    "journal": "dvm360",
    "date": "2026-10-15",
    "title": "RECOVER first aid guidelines give veterinary teams a playbook for coaching clients",
    "abstract": "New guidelines from RECOVER are written for veterinary teams to teach owners, handlers, and other caregivers what to do in the minutes before a pet reaches the clinic.",
    "url": "https://www.dvm360.com/view/recover-first-aid-guidelines-give-veterinary-teams-a-playbook-for-coaching-clients",
    "doi": null,
    "pmid": null,
    "category_hint": "media_guideline",
    "collected_by": "dvm360",
    "priority": 0
   },
   {
    "id": "feed:WSAVA:https://wsava.org/updates/advancing-dental-care-worldwide-our-updated-global-dental-guidelines-are-here/",
    "source": "WSAVA RSS",
    "journal": "WSAVA",
    "date": "2026-09-24",
    "title": "Advancing Dental Care Worldwide: Our Updated Global Dental Guidelines Are Here",
    "abstract": "Our updated 2026 Global Dental Guidelines are now available, providing veterinary professionals worldwide with practical, evidence-based guidance to support the prevention, diagnosis and treatment of oral and dental disease in companion animals.",
    "url": "https://wsava.org/updates/advancing-dental-care-worldwide-our-updated-global-dental-guidelines-are-here/",
    "doi": null,
    "pmid": null,
    "category_hint": "guidelines",
    "collected_by": "feed_wsava",
    "priority": 0
   },
   {
    "id": "feed:WSAVA:https://wsava.org/updates/update-on-the-working-group-following-erratum-published-in-march-2025/",
    "source": "WSAVA RSS",
    "journal": "WSAVA",
    "date": "2026-08-29",
    "title": "Update on the Working Group following Erratum Published in March 2025",
    "abstract": "WSAVA has published an update on the Multidisciplinary Reproduction Control Working Group following the Erratum published in March 2025.",
    "url": "https://wsava.org/updates/update-on-the-working-group-following-erratum-published-in-march-2025/",
    "doi": null,
    "pmid": null,
    "category_hint": "guidelines",
    "collected_by": "feed_wsava",
    "priority": 0
   }
  ],
  "disease_alerts": [
   {
    "id": "pmid:42885913",
    "source": "PubMed",
    "journal": "Microbiology resource announcements",
    "date": "2026-10-16",
    "title": "Whole genome sequences of highly pathogenic H5N1 avian influenza viruses detected in felines in Bangladesh.",
    "abstract": "Whole-genome sequences of three highly pathogenic H5N1 avian influenza viruses detected in cats in Bangladesh during 2025-2026 are reported. Phylogenetically, two strains grouped within clade 2.3.2.1a, and the other within the clade 2.3.4.4b. The isolates harbored mutations in key polymerase and HA markers associated with mammalian adaptation and virulence.",
    "url": "https://pubmed.ncbi.nlm.nih.gov/42885913/",
    "doi": "10.1128/mra.00835-26",
    "pmid": "42885913",
    "authors": [
     "Sajedul Hayat",
     "Shukes Chandra Badhy",
     "Mohammad Enayet Hossain"
    ],
    "collected_by": "pubmed_alerts",
    "priority": 54
   },
   {
    "id": "pmid:42886674",
    "source": "PubMed",
    "journal": "PloS one",
    "date": "2026-01-01",
    "title": "Owned dog population profile, dog ownership and bite risk determinants: Key steps to rabies control in Antananarivo, Madagascar.",
    "abstract": "Rabies remains a significant public health threat in Madagascar, with dog-mediated transmission causing approximately 1,000 human deaths annually. In Antananarivo, the capital city, control efforts are hindered by limited up to date knowledge on the dog population. This study aims to provide updated estimates of the owned dog population characteristics, identify determinants of ownership, and assess dog bite incidence and risk factors to guide effective vaccination and prevention strategies. Between 2023 and 2025, a longitudinal door‑to‑door household survey was conducted across 21 fokontany (administrative units) in Antananarivo. Of 2,518 surveyed households, 30.5% reported dog ownership, with 1,273 dogs recorded, yielding an estimated dog‑to‑human ratio of 1:9. The owned dog population was predominantly male (63.6%), with a median age of three years. Survival analysis in the selected study site indicated a median lifespan of 4.4 years and an annual mortality hazard of 16%. Vaccination coverage was low: 64.2% of owned dogs had never been vaccinated, primarily due to owners' time constraints, lack of awareness about the need for dog rabies vaccination, and financial barriers. Ownership was positively associated with household location and size, household head's age, education and income. No significant difference in bite risk was observed between dog‑owning and non‑dog‑owning households, whereas households with children under 15 years experienced a significantly higher risk. Rabies elimination among the owned dog population in Antananarivo requires sustained, context‑adapte",
    "url": "https://pubmed.ncbi.nlm.nih.gov/42886674/",
    "doi": "10.1371/journal.pone.0360417",
    "pmid": "42886674",
    "authors": [
     "Marie Hermelienne Volasoa",
     "Santatriniaina Michel Joharison Andrianarivelo",
     "Katerina Albrechtova"
    ],
    "collected_by": "pubmed_alerts",
    "priority": 50
   },
   {
    "id": "gnews:https://news.google.com/rss/articles/CBMiogFBVV95cUxPcF9fTGEyZmM4c01WQmtHX2stTDRNSzdMOUtuUDV3ekRuelBPbHE0UXAxZUlrSGFUSmNZTjdDaXk2RTdwQWViQ0VvcTRzc0I2M0lvOVNYb3BidF9JUnBHX2U1MklHS3Z",
    "source": "Google News",
    "journal": "Google News: dog parvovirus outbreak",
    "date": "2026-10-19",
    "title": "Deadly feline disease outbreak kills 20 cats in Rivière-du-Loup, Que. - CBC",
    "abstract": "Deadly feline disease outbreak kills 20 cats in Rivière-du-Loup, Que.&nbsp;&nbsp;CBC",
    "url": "https://news.google.com/rss/articles/CBMiogFBVV95cUxPcF9fTGEyZmM4c01WQmtHX2stTDRNSzdMOUtuUDV3ekRuelBPbHE0UXAxZUlrSGFUSmNZTjdDaXk2RTdwQWViQ0VvcTRzc0I2M0lvOVNYb3BidF9JUnBHX2U1MklHS3ZhZEVYcXhwSXRhbEIybU9WdmFOYW9sMDlHQjVYc1VDeTlrTHdmQzhBTERzRThlVEpWMVNVTFFRMUNoZ0E?oc=5",
    "doi": null,
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    "collected_by": "gnews",
    "priority": 0
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   {
    "id": "dvm360:https://www.dvm360.com/view/dvm360-live-returns-with-a-doj-pet-food-lawsuit-screwworm-surveillance-and-more",
    "source": "dvm360",
    "journal": "dvm360",
    "date": "2026-10-16",
    "title": "dvm360 Live! returns with a DOJ pet food lawsuit, screwworm surveillance, and more",
    "abstract": "Adam Christman, DVM, MBA, returns as host for season 3, featuring a roundup of recent veterinary news and an appearance by guest Steve Mehler, DVM, DACVS.",
    "url": "https://www.dvm360.com/view/dvm360-live-returns-with-a-doj-pet-food-lawsuit-screwworm-surveillance-and-more",
    "doi": null,
    "pmid": null,
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    "collected_by": "dvm360",
    "priority": 0
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    "source": "Google News",
    "journal": "Google News: dog parvovirus outbreak",
    "date": "2026-10-13",
    "title": "Dog centre owner 'sick' over parvovirus concerns - Yahoo",
    "abstract": "Dog centre owner 'sick' over parvovirus concerns&nbsp;&nbsp;Yahoo",
    "url": "https://news.google.com/rss/articles/CBMihwFBVV95cUxOSTl1V2FBS25Fel9lQlFLNF9aT0kxWm5xRktBcERGNWh5X2tQVFBKbHM4V2xEdXJ2MDFBdmxRRFBZaHAwRWhvLXk0MEZSb29sZ3h1M0xFX0R0MkJHSXFBWV9YQnFXc0R3VEdBOWpqVXFxdWJmdjNfbmNicGhWTS0zV1EyMm5reVE?oc=5",
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   }
  ]
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